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Featured Speaker

Thomas Kodadek

Thomas Kodadek
The Scripps Research Institute

Talk Title

Synthesis and Screening of Libraries of Conformationally Constrained, Peptoid-Inspired Oligomers

There is great interest in developing probe molecules and drug leads that target the so-called "undruggable proteome." This is perhaps better described as proteins that lack deep molecular crevices that can be targeted with "Rule of Five" small molecules.

It is generally acknowledged that addressing difficult targets, such as those that function via protein-protein interactions, PPIs, will require larger molecul…