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Featured Speaker

Michelle Arkin

Michelle Arkin
University of California at San Francisco

Talk Title

Tackling Challenging Drug Targets using Fragment-Based Ligand Discovery

Many potential drug targets are known to be relevant for disease, but have been ‘undruggable’ by current approaches. Our lab seeks to understand to what extent this failure has been due to the features of the biological target vs the methodologies used to discover small-molecule modulators.

In particular, we have focused on protein-protein interactions and the larger networks controlled by these interaction…